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IMPAACT4HIV

On this page, explore how research drives progress in AHD care — with access to key studies, clinical trial results, guidelines, and insights shaping policy and practice across sub-Saharan Africa.

This page offers clinical resources, training tools, patient support, policy content, multimedia, and accessibility features — all designed to support comprehensive care and education.

Histoplasmosis Fact Sheet

Histoplasmosis is a serious fungal infection that primarily threatens people with weakened immune systems. Histoplasmosis is an infection caused by a fungus that lives in soil, especially where there are bird or bat droppings. People can get infected when they breathe in dust containing the fungus during activities like farming, gardening, or construction. Download document

Advanced HIV Disease Pocket Reference for Community Healthworkers

This Is a reference book for all communities, community health workers, and partners involved in the HIV response. It provides practical guide to support a holistic response to Advanced HIV disease in children and adults. Recommendations are guided by the WHO and informed by emerging lessons on community engagement on the IMPAACT4HIV project. This guide […]

The Advanced HIV Community Advocacy Toolkit 2026

The Community Engagement and Advocacy Toolkit is designed to equip community organizations, advocates, peer supporters, and civil society partners with practical knowledge, tools, and strategies to strengthen community-led responses to Advanced HIV Disease (AHD). It supports meaningful engagement with communities, promotes early identification and linkage to care, strengthens advocacy for equitable access to quality AHD […]

IMPAACT AHD Commodities Guide R1

This guide was created for the people who are closest to the AHD problem and its solution: nurses, community health workers, clinic staff, civil society, and community-based organisations. It brings together all the essential tools to screen, test, treat, and prevent AHD, the most common and serious infections affecting people with AHD. Download document

From Evidence to Action: Using Community-Led Monitoring to Strengthen AHD Services

Country & district/site: Mozambique – Matola Provincial Hospital and Manhiça Health CentreOrganisation: MATRAMMain AHD area: CLM/Advocacy, AHD Identification, Health Systems Strengthening What Was the Problem? While many people living with HIV were receiving antiretroviral treatment, community members continued to report concerns about the quality and completeness of Advanced HIV Disease services. There was limited information […]

How Community Support Helped Raquel Take Control of Her HIV Treatment

Country & district/site: Mozambique Organisation: MATRAM Main AHD area: ART Adherence, Adolescent HIV What Was the Problem? Raquel, a 12-year-old girl living with HIV, had acquired HIV at birth and was struggling to adhere to treatment. Her mother worked long hours and was rarely at home, leaving much of Raquel’s care to a neighbour who […]

When the Activists Came Knocking

Country & district/site: Mozambique – Tsalala, Matola CityOrganisation: MATRAMMain AHD area: Paediatric AHD, Referral & Linkage, ART Adherence What Was the Problem? In the Tsalala neighbourhood of Matola City, a young mother was struggling to care for three children on her own after separating from their father. Her youngest child, six-month-old Gerson, had been born […]

Beyond the Clinic Walls – When Survival Comes Before Health

Country & Site South Africa – Khuma, Stilfontein Organisation Lefika La Ka Main AHD Area Referral & Linkage, CLM/Advocacy What Was the Problem? As part of community tracing activities, the Lefika La Ka team was working to locate individuals who had interrupted HIV treatment and were no longer attending health facilities for medication collection. The […]

When HIV Meets Poverty, Disability and Family Breakdown

Country & Site South Africa – Khuma, Stilfontein Organisation Lefika La Ka Main AHD Area Paediatric AHD, ART Adherence, CLM/Advocacy What Was the Problem? During a household tracing visit, the community team arrived at the address recorded by the health facility only to discover that the child they were searching for no longer lived there. […]

The Child Who Slipped Through the Gaps

Country & Site South Africa – Khuma, Stilfontein Organisation Lefika La Ka Main AHD Area Paediatric AHD, Referral & Linkage, ART Adherence What Was the Problem? As part of household visits to children living with HIV who were experiencing poor viral suppression, the community team set out to visit three households identified by the health […]

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