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IMPAACT4HIV

On this page, explore how research drives progress in AHD care — with access to key studies, clinical trial results, guidelines, and insights shaping policy and practice across sub-Saharan Africa.

This page offers clinical resources, training tools, patient support, policy content, multimedia, and accessibility features — all designed to support comprehensive care and education.

Histoplasmosis Fact Sheet

Histoplasmosis is a serious fungal infection that primarily threatens people with weakened immune systems. Histoplasmosis is an infection caused by a fungus that lives in soil, especially where there are bird or bat droppings. People can get infected when they breathe in dust containing the fungus during activities like farming, gardening, or construction. Download document

Tracking cryptococcal meningitis to monitor HIV program success during the Treat-All era: an analysis of national data in Botswana

James Milburn 1 2, Ookeditse Ntwayagae 3, Rachita Suresh 1, Kebatshabile Ngoni 1, Cassie Northcott 1, James Penney 1, Matthew Kinsella 1, Imogen Mechie 1, Samuel Ensor 1, Goitseone Thamae 1, Tshepo Leeme 1, David S Lawrence 1 2, Tony Chebani 4, Daniel Grint 5, Mark W Tenforde 6, Ava Avalos 1, Dinah Ramaabya 4, Justus Ogando 7, Margaret Mokomane 8, Madisa Mine 9, Joseph N Jarvis 1 2 Affiliations Expand Abstract Background: Cryptococcal meningitis (CM) causes substantial mortality in African countries with a high prevalence of human immunodeficiency virus (HIV), despite advances in disease management and increasing antiretroviral therapy (ART) […]

Implementation of a rapid diagnostic assay package for cryptococcosis, histoplasmosis and tuberculosis in people living with HIV in Paraguay

Gloria Aguilar, Gladys Lopez, Omar Sued,  Narda Medina, Diego H. Caceres, Jose Pereira, Alexander Jordan, Virgilio Lezcano, Cristina Vicenti, Gustavo Benitez, Tania Samudio & Freddy Perez    Abstract Background Opportunistic infections (OIs) are common causes of mortality among people living with HIV (PLHIV). We determined prevalence and 30-day mortality due to histoplasmosis, cryptococcosis, and TB in PLHIV with advanced HIV disease (AHD).   […]

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